The Liberty Blue™ 2.0 is an ultra-efficient microwave peptide synthesizer, delivering high-quality peptides with record low waste generation and synthesis times. Through partnering CEM’s patented and published No-Wash methodology with flexible and intuitive system controls, the Liberty Blue 2.0 opens up a world of more efficient, high-yielding, and structurally complex syntheses than ever thought possible.The Liberty Blue 2.0 features the latest in engineering for fluidic deliveries, true internal temperature feedback control, and software control with 21 CFR Part 11 compliance.

• CarboMAX™ coupling chemistry
• Microwave deprotection and coupling
• Nitrogen Headspace Flushing

• <4 minutes per amino acid (AA) addition (includes coupling through deprotection, scales under 0.5 mmol)
• <6 mL waste generated per AA addition (includes coupling through deprotection, scales under 0.2 mmol )
• 0.005 to 5 mmol synthesis scale range
• HT accessories available for queueing up to 12 syntheses
• 21CFR Part 11 compliant software

Ultra Efficient – Solid Phase Peptide Synthesis (UE-SPPS)

New “No Wash” approach, same clean peptides.

With this Liberty system comes the revolutionary UE-SPPS methodology; total wash elimination. Through a remarkable combination of methodology optimization, reagent selection, and engineering advancements, CEM’s “No Wash” technology reduces waste production by up to 95%, and all without sacrificing synthesis yield and purity.

A new level of peptide purity

The Liberty Blue 2.0 provides the ability to make even higher purity peptides than previously possible with the original Liberty Blue system. This is based on advances in the system fluidics, reaction vessel environment, and chemistry methodology.

• Optimized microwave chemistry methodology with ProTide resins
• Cleanest reaction environment with updated headspace flushing technology
• More direct optimized flow paths
• Digitally variable N2 control for optimized bubbling, purging, and draining

More peptide synthesis, less hands-on time.

Queue up to 4 sequential syntheses with the optional HT4 accessory, and up to 12 sequential syntheses with the HT12 accessory.

Each peptide is available immediately, eliminating purification bottlenecks common with batch syntheses.