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Agilent

xCELLigence RTCA MP

Short product description
Obtain continuous cell assay data points using label-free methods, in a 6 x 96-well format

Information

Overview

The xCELLigence RTCA MP instrument uses biosensors to continuously monitor cell behavior in a 6 x 96-well format. Obtain continuous cell assay data points using label-free methods. This multiple plate format is ideal for cell killing and immunotherapy applications such as antibody dependent cytotoxicity, bispecific T cell engagers, checkpoint inhibitors, NK cells, T cells, B cells, oncolytic viruses.

The MP model can host up to six 96-well electronic microplates (E-Plate 96) which can be run in parallel or independently of one another. This flexible plate batch processing allows for maximum productivity for multiple users. The instrument operates in a standard CO2 cell culture incubator and the control unit is housed outside the incubator. Easy-to-use intuitive software allows for real-time control and monitoring of the instrument and includes real-time data display and analysis functions.

Combining impedance with microscopy?
check out the Agilent xCELLigence RTCA eSight.

• Observe the tumor cell response to immune effector cells in real-time
• Obtain continuous immune cell killing timepoints during the entire experiment.
• RTCA provides a continuous quantitative readout of cell number, proliferation rate, cell size/shape, and cell-substrate attachment quality

 

” The xCELLigence system adds on our capabilities enabling real-time monitoring of cytotoxicity of cell therapies and antibodies/bispecifics against tumor cell lines or healthy primary cells. Performing co-cultures with these cell types will allow us to better assess in vitro efficacy and safety of various therapies on a wider range of diseased and healthy tissues.”

Charles River

The Netherlands

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