Agilent produces a number of cell analysis instruments designed to give life science researchers and drug discovery research scientists better insights into cellular function. The Agilent cell analysis portfolio covers many measurement modalities, including energy metabolism, real-time cell viability, contractility, movement (impedance), and flow cytometry.
xCelligence RTCA Analyzers
The xCELLigence System from ACEA Biosciences (now Agilent) is a microelectronic biosensor system for cell -based assays, providing dynamic, real-time, label-free cellular analysis for a variety of research applications in drug development, toxicology, cancer, medical microbiology,and virology.The xCELLigence system uses specially designed microtiter plates containing interdigitated gold microelectrodes to noninvasively monitor the viability of cultured cells using electrical impedance as the readout. The continuous monitoring of cell viability by the xCELLigence system makes it possible to distinguish between different perturbations of cell viability, such as senescence, cell toxicity (cell death), and reduced proliferation (cell cycle arrest). In addition, the time resolution of the xCELLigence system allows for the determination of optimal time points to perform standard cell viability assays as well as other end-point assays to understand the mode of action.