BioSpa Software controls all aspects of the BioSpa 8 Automated Incubator, including temperature and gas control and monitoring, along with humidity monitoring. The software features customizable text or email notifications and alerts, relieving the need for onsite monitoring. The software’s session timelines and environmental reports allow quick scrutiny of the process and system status. BioSpa software communicates with Gen5 and LHC software to control integrated imaging, detection and liquid handling instruments.

BioSpa Automated incubator with 8-plate capacity, incubation to 45 °C, with control and monitoring. Includes BioSpa software and one alignment kit. BIOSPAG Automated incubator with 8-plate capacity, incubation to 45 °C and CO2/O2 control and monitoring, water pan and humidity monitoring. Includes BioSpa software and one alignment kit.

BioSpa Live Cell Imaging system can be comprised of of BioSpa 8 Automated Incubator, along with other compatible imagers, washers and dispensers: • Cytation 5 Cell Imaging Multi-Mode Reader • Cytation 1 Cell Imaging Multi-Mode Reader • EL406 Washer Dispenser • 405 LS Washer • 405 TS Washer • MultiFlo FX Multi-Mode Dispenser

Complete workflow automation, sample prep to detection BioSpa8 handles up to 8 microplates, Petri and cell culture dishes and T25 flasks during automated processes, running up to 2 weeks. Place the labware in BioSpa’s drawers, and the gripper moves to the connected imaging, detection and liquid handlers as scheduled in the BioSpa software. Temperature, CO2/O2 control; humidity monitoring Critical physiological conditions are maintained in BioSpa: Incubation to 45 °C, CO2/O2 control and humidity monitoring facilitate live cell processes. BioSpa software continuously records the environment conditions to ensure assay success. Records environment conditions; automated alerts BioSpa software monitors and records the system and environment conditions throughout the entire runtime. Customizable text and email notifications allow you to walk away from the process with confidence. OnDemand Mode For simple, efficient imaging or detection protocols, OnDemand mode allows labware to be added or removed at any time, without interrupting operations in process. Multiple users can be defined in the system and each user can visually track their own experiment’s progress on the dynamic timeline. Compact for benchtop use, or for optional biosafety cabinet use When the workflow calls for sterile conditions, BioSpa and integrated instruments is compact enough to fit in a biosafety enclosure. Uncomplicated software and simple integration BioSpa software integrates seamlessly with Gen5 and LHC software to provide easy and intuitive scheduling for short and long-term processes.

Unattended workflow automation BioSpa 8 handles up to 8 microplates, Petri and cell culture dishes and T25 flasks during automated processes, running up to 2 weeks. Place the labware in BioSpa’s drawers, and the gripper moves to the connected imaging, detection and liquid handlers as scheduled in the BioSpa software. Environmental controls for live cell assays Critical physiological conditions are maintained in BioSpa: Incubation to 45 °C, CO2/O2 control and humidity monitoring facilitate live cell processes. BioSpa software continuously records the environment conditions to ensure assay success. Customizable text and email notifications allow you to walk away from the process with confidence. Fluorescence, high contrast brightfield, color brightfield and phase contrast imaging BioSpa 8 integration with Cytation 5 brings powerful image collection and analysis tools to the automated workflow. With six turret positions for objectives ranging from 1.25x to 60x, four channels plus brightfield, and more than 15 colors available, Cytation 5 brings unsurpassed capabilities to automated digital microscopy for many long-term live cell imaging processes. OnDemand Mode For simple, efficient imaging or detection protocols, OnDemand mode allows labware to be added or removed at any time, without interrupting operations in process. Multiple users can be defined in the system and each user can visually track their own experiment’s progress on the dynamic timeline. Advanced cell-level analysis with Gen5 Software Gen5 Microplate Reader and Imager software is available in several editions to meet the imaging and analysis requirements of many applications. From basic automated cell counting to advance capabilities including dual masks for nucleus and cytoplasm identification, Gen5 offers complete and powerful quantitative data analysis in and uncomplicated interface. Washing and media replacement BioSpa 8 is compatible with BioTek’s MultiFlo FX and EL406 for plate washing and media exchange. Adding a combination washer dispenser or washer to the BioSpa 8 and Cytation integrated system provides complete automated process from sample prep through image analysis. • Up to 60x magnification and 4 color channels covers a range of applications • Single- and multi-color, montage, time lapse and automated z-stacking • Powerful image processing: z-projection, digital phase contrast and image stitching • Compact system fits in biosafety cabinet for the ultimate cell assay protection • Lidded plate handling, easy maintenance